Number-one singles[]
| Issue Date | Song | Artist(s) | Sales |
|---|---|---|---|
| 5 January | "Sound of the Underground" | Girls Aloud | |
| 12 January | "Beautiful" | Christina Aguilera | |
| 19 January | |||
| 26 January | "You Take It" | 3G | |
| 2 February | |||
| 9 February | |||
| 16 February | "In da Club" | 50 Cent | |
| 23 February | "All the Things She Said" | t.A.T.u | |
| 2 March | |||
| 9 March | |||
| 16 March | "Ignition (Remix)" | R. Kelly | |
| 23 March | |||
| 30 March | |||
| 6 April | "Hope" | 3G | |
| 13 April | |||
| 20 April | |||
| 27 April | |||
| 4 May | "Rock Your Body" | Justin Timberlake | |
| 11 May | "Bring Me to Life" | Evanescence | |
| 18 May | |||
| 25 May | |||
| 1 June | |||
| 8 June | "Go, Go, Go" | Radio Star | |
| 15 June | "Crazy in Love" | Beyonce featuring Jay-Z | |
| 22 June | |||
| 29 June | |||
| 6 July | |||
| 13 July | "If You're Not the One" | Daniel Bedingfield | |
| 20 July | |||
| 27 July | "Cry Me a River" | Justin Timberlake | |
| 3 August | "P.I.M.P." | 50 Cent featuring Snoop Dogg | |
| 10 August | "Where Is the Love? | The Black Eyed Peas | |
| 17 August | |||
| 24 August | |||
| 31 August | |||
| 7 September | |||
| 14 September | "Fighter" | Christina Aguilera | |
| 21 September | "Baby Boy" | Beyonce featuring Sean Paul | |
| 28 September | |||
| 5 October | "White Flag" | Dido | |
| 12 October | |||
| 19 October | |||
| 26 October | "Clocks" | Coldplay | |
| 2 November | "Rock Me Back" | XoX | |
| 9 November | |||
| 16 November | "No Way" | Radio Star | |
| 23 November | |||
| 30 November | "Milkshake" | Kelis | |
| 7 December | |||
| 14 December | |||
| 21 December | "Hey Ya!" | OutKast | |
| 28 December |